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UV SPECTROPHOTOMETRIC ESTIMATION OF PHENAZONE IN BULK AND TABLET DOSAGE FORM BY AUC METHOD
Saurabh S. Arale*, Manisha S. Phoujdar, Shwetal P. Vassa
ABSTRACT A simple, precise, accurate, and economical UV visible spectrophotometric method has been developed for estimation of Phenazone drug by AUC method. The standard and sample solutions were prepared by using double distilled water as a solvent. Quantitative determination of the drug was performed at wavelength range 232-252 nm. The linearity was established over the concentration range of 10-30 μg/ml for Phenazone with correlation coefficient value of 0.9998. Precision studies showed that % relative standard deviation was within range of acceptable limits. The mean percentage recovery was found to be 99.905%. The proposed method has been validated as per ICH guidelines Keywords: Phenazone, UV visible spectrophotometry, AUC, Method Validation. [Download Article] [Download Certifiate] |