Abstract

A REVIEW ON: - PHARMACOTHERAPY OF HYPERTENSION

Dhananjay D. Narsale*, Hemant V. Kamble, Santosh A. Waghmare and Sonal S. Ithape

ABSTRACT

Hypertension is the most common modifiable risk factor for death and disability including stroke, accelerated coronary and systemic atherosclerosis, heart failure, chronic kidney disease, lowering the BP with antihypertensive drugs, and reducing the target organ damage and prevalence of the occurrence of cardiovascular disease. Hypertension is defined as systolic bp is ≥130 mm/hg or diastolic bp is ≥80 mm/hg. bp should be lower than 130/80 mm/hg in patient with chd, chf, after renal transplantation, diabetes mellitus and stroke. Recommended lifestyle modification included restriction of dietary sodium intake, weight loss if patient is overweight, regular exercise, moderate alcohol intake and increase consumption of potassium rich foods. the initial antihypertensive agent should be generally selected from one of the following four classes—thiazide diuretics, ace inhibitors, arbs, and calcium channel blockers, shown to reduce cardiovascular events.

Keywords: Hypertension, Cardiovascular diseases, Mechanism, Treatment Antihypertensive Drugs Therapy.