Abstract

OVERVIEW ON VITILIGO (SKIN DISEASE)

Niraj Y. Jadhav*, Krishna S. Jaju, Pratiksha Mhaske and Pallavi Phalke

ABSTRACT

A disease that causes the loss of skin colour in blotches. Vitiligo occurs when pigment-producing cells die or stop functioning. It is an acquired skin disorder caused by the disappearance of pigment cells from the epidermis that gives rise to well defined white patches which are often symmetrically distributed. The lack of melanin pigment makes the lesional skin more sensitive to sunburn. Vitiligo can be cosmetically disfiguring and it is a stigmatizing condition, leading to serious psychologic problems in daily life. It occurs worldwide in about 0.5% of the population and it occurs as frequently in males as it does in females. The cause is unknown, but might involve genetic factors, autoimmunity, neurologic factors, toxic metabolites, and lack of melanocyte growth factors.

Keywords: ? Grafting ? Melanocytes ? White patches ? genetically occur ? Depigmentation.