Abstract

FORMULATION, DEVELOPMENT & EVALUATION OF ULTRASONIC GEL

Kishor S. Rathi*, Krushnai K. Patel, Keshav B. Rajput, Yashkumar S. Patil, Dr. Ravindra R. Patil

ABSTRACT

Every hospital and healthcare facility uses ultrasound screening on a regular basis. In all ultrasound procedures, ultrasound gel is used as a coupling medium to substitute air between the transducer and the patient's skin, other readily available chemicals were also used, but they do not harm the epidermis. The required physicochemical properties, including visual clarity, homogeneity, transparency, skin irritation, antibacterial activity, pH, stability, spreadability, conductivity, acoustic impedance, viscosity, and cost, were assessed to support the formulations' efficacy. Additionally, a comparison research using ultrasound gel that is readily available in stores as a control was also carried out. All samples displayed superb clarity and no signs of microbial development. Only F2 generated images that were comparable to those created by commercial ultrasound gel and complied with all of the specifications for commercial ultrasound gel. Thus, this mixture could be used to take images in clinics and medical facilities instead of pricy commercial ultrasound gel. The results showed that the formulated ultrasound gel and its ingredients were consistent in quality and can be easily used. The formulated ultrasound gel was found to be superior to commercially available gel in part of pain management score. It is concluded that the formulated ultrasound gel can be used for ultrasound physiotherapy treatment.

Keywords: Ultrasonography, Aloevera Gel, Methylparaben, Carbapol 940.