Abstract

FORMULATION AND EVALUATION OF ANTIFUNGAL POWDER

Tiwari Nishant*, Gehlot Suman, Khare Nripen Prakash and Shrivastava Satyaendra

ABSTRACT

The purpose of the present study was to formulate and evaluate antifungal powder to give fungicidal or fungistatic effect. The powder was prepared by using the API (clotrimazole), chemicals like menthol, zinc oxide, boric acid and salicylic acid were utilized as excipients and talc powder was utilized as a base. The powder was prepared by homogeneous mixing of all the excipients. Powder was evaluated for different parameters like, organoleptic properties, powder flow properties (tapped density, bulk density, angle of repose, Hausner’s ratio and carr’s index), moisture content test or hygroscopy, skin irritancy test, and stability test. Powder ingredients showed significant results in evaluation parameters. Based on the results, it is suggested that the product is safely stable at room temperature.

Keywords: Clotrimazole, Salicylic acid, Antifungal Powder.