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All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
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SCREENING FOR POTENTIAL ANTI-ALZHEIMER’S COMPOUNDS FROM ANGELICA SINENSIS EXTRACTIONS
Nguyen Khanh Linh and Nguyen Hoang Khue Tu*
ABSTRACT
Alzheimer's disease (AD) is a neurodegenerative disease in which overexpression in the level of Amyloid-β (Aβ) and Phosphorylated Tau protein (P-tau) is contained in extracellular plaques and intracellular neurofibrillary tangles, respectively. Besides, natural bioactive nutrients are present in herbs, widely used as specific compounds to prevent major neurodegenerative diseases instead of approved drugs such as Alzheimer, dementia, Parkinson, and so on. Recent studies have discovered a new perspective value of Angelica sinensis (A. sinensis) in clinical medicine treatment, especially in neurodegenerative diseases. Keywords: Angelica sinensis extractions, gas chromatography-mass spectrum, molecular docking, in silico pharmacokinetics, anti-Alzheimer. [Download Article] [Download Certifiate] |