Abstract

OVERVIEW ON HPTLC: HIGHLY SOFISTICATED ANALYTICAL INSTRUMENT FOR QUALITATIVE AND QUANTITATIVE ANALYSIS

Aditya A. Bogar*, Vinayak B. Jamkar, Akshay D. Tuljapure, Suchita P. Ramteke and Chandrakant D. Chakote

ABSTRACT

Planar chromatography includes High Performance Thin Layer Chromatography (HPTLC), the most sophisticated version of instrumental Thin Layer Chromatography (TLC). One of the most effective analytical techniques available today, HPTLC is equally effective for qualitative and quantitative applications. HPTLC is more practical than both TLC and High performance Liquid Chromatography (HPLC). HPTLC is not only instrumental TLC but an entire concept that includes widely defined technique based on established approach. This is because HPTLC is independent of sample application, chromatogram generation, detection, etc. It is a software-controlled gadget. In this review post, we covered its basics, the instrument types utilized in HPTLC, the full HPTLC methodology, applications, and how HPTLC is superior to TLC.

Keywords: HPTLC, analytical techniques, Chromatogram, HPLC, TLC.