Abstract

A REVIEW ON ANTI-MALARIAL DRUG DISCOVERY AND ITS SCREENING METHOD

Prem Shankar Mishra*, Dr. Himanshu Sharma, Rakhi Mishra, Dr. S.K.Gupta

ABSTRACT

Malaria has been one of the most prominent and ancient diseases which has been profiled and studied. A lot of effort has been done for the design and discovery of anti-malarial drugs. The anti-malarial drug discovery and its screening are urgently needed. Our aim must be to Design safe and affordable noble drugs to control the spread of malarial parasites that are resistant to existing agents. Therapeutic efficacy and toxicity are important for the design and synthesis of compounds, while a minor effort has been done to review and asses the screening of anti-malarial drug-efficacy. In this review, we suggest different in-vitro and invivo screening for anti-malarial drugs, and evaluate different process for new compounds from drug discovery to development.

Keywords: anti-malarial drugs, drug-efficacy, in-vitro.