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STUDY OF MEDICATION COMPLIANCE, ADVERSE DRUG REACTIONS AND QUALITY OF LIFE OF DIABETIC PATIENTS
K. Haritha, *CH. Vasavi, B. Devi Prasad, K. Saravanan, S. Selvamuthu Kumaran
ABSTRACT
Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia and abnormalities in carbohydrate, fat, and protein metabolism. It results from defects in insulin secretion, insulin sensitivity, or both. Aim is to study the Medication compliance, Adverse Drug Reactions and Quality of life of Diabetic patients.Method involves a non-invasive, prospective, observational study was conducted at Rajah Muthiah Medical College Hospital.In this study 52% patients rated themselves as complaint. 36% patients rated themselves non- compliant. At the end of study more number of patients 68% found to be complaint when compared to baseline. Out of 75 patients, 35 were observed with ADR. Based on age, more number of ADRs was observed in the age group of 51-60 years. In 35 patients, 14 were maleand 21 were female,29 had ADR before admission to hospital and 6 patients experienced ADR during hospital stay.When prescribing pattern was analyzed, the patients were prescribed with Sulphonylureas, Biguanides, Insulin and combination of Sulphonyl urea and Biguanide.The common ADR is Hypoglycemia and it is followed by Gastric irritation, Gidiness, Allergic skin reactions, Headache, Vomiting Abdominal distension and Asthymia. During the treatment of DM, drugs given to 16 were stopped due to ADR. For 8 patients drug causing ADR were identified and substituted with suitable drugs. For 11 patients the medication profile has been totally changed. The Mean±SEM scores for physical, physiological, social and environmental components before counseling was found to be lesser than the post counseling.This study helps to understand the effects of drugs and adverse drug reaction of anti-diabetic drugs and helps to initiate drug safety program for the hospital which monitor and work towards minimizing the incidence of ADRs there by promoting rational use of drug. Keywords: Diabetes Mellitus, adverse drug reactions, quality of life, medication compliance and self-assessment method [Download Article] [Download Certifiate] |