Abstract

ORODISPERSIBLE TABLETS: A NEW TREND IN DRUG DELIVERY

Chekuri Anusha*, Gudise Sita Mahalakshmi, Brahmaiah Bonthagarala, M. Mohan Varma and K. S. Nataraj

ABSTRACT

The oral route is regarded as the most convenient and safest approach in the pharmaceutical industry. Orodispersible tablets (ODTs) are solid dosage forms for drugs that dissolve in less than a minute in the mouth, leaving a residue that is simple to swallow. This dose form contains superdisintegrants, which promote rapid disintegration when saliva is present and facilitate easy swallowing. ODTs are a great option for individuals in both the pediatrics and elderly populations. Orodispersible drug delivery methods are widely utilized to increasing the bioavailability of numerous drugs. Orodispersible tablets are made by direct compression, freeze drying, sublimation, mass extrusion, and the cotton candy process, among other cutting-edge techniques. Since these tablets dissolve instantly in the tongue, taste is a crucial component. ODTs are assessed using the following criteria, including hardness, friability, disintegration, and dissolution tests. The production of controlled release orodispersible tablets is now possible thanks to a variety of technologies, which expands the therapeutic uses for this drug delivery system. These pills are also referred to as mouth-dissolving and quick-dissolving tablets. In this review article, we can concentrate on the ideal qualities, difficulties, benefits, drawbacks, conventional methods, patented technologies, and assessment of orodispersible tablets.

Keywords: Orodispersible tablets (ODTs), Tablet porosity, Friability, Hardness.