Abstract

A BRIEF REVIEW ON HEPATOPROTECTIVE DRUG

*Akshay N. Gudadhe, Snehal Y. Chakre, Pratik D. Vaidya and Akash P. Mhala

ABSTRACT

Liver has a wide range of function including detoxification, protein synthesis, and production of biochemical necessary for digestion and synthesis as well as breakdown of small and complex, many of which are necessary for normal vital function. Hepatic disease is term for a collection of conditions disease and infection that affect the cells, tissues, structure or functions of the liver. Hepatoprotective drugs means the drugs that are prevent the liver disease. The liver is an organ that is located in the upper right hand side of the abdomen, mostly behind the rib cage. The maintenance of a healthy liver is vital to overall health of the human beings. Since the liver is involved in almost all biochemical processes and there are many different diseases that will affect it. The liver is often abused by environmental toxins, which are eating habits, alcohol and overdose of certain drugs which can damage and weaken the liver and eventually lead to many diseases. Medicinal herbs are significant source of hepatoprotective drugs. Liver diseases are a major health problem worldwide, making it necessary to develop new molecules that help counteract or prevent such diseases. On account of this fact, investigations aiming to obtain natural and/or synthetic compounds possessing Hepatoprotective activity have been undertaken. The development of new drugs consists of a variety of steps, ranging from the discovery of the pharmacological effects in cellular and animal models, to finally demonstrate their efficacy and safety in humans. In this review, we will briefly discuss hepatoprotective drugs.

Keywords: Hepatoprotective, Liver, Hepatoprotective herbs.