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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

AN INVITRO CYTOTOXICITY STUDY OF CNIDOSCOLUS CHAYAMANSA MCVAUGH ON SELECTED CELL LINES

Kulathuran Pillai Kumarasamy*, Narayanan Nallaperumal, Chidambaranathan Natarajan and Jegan Nallamadan

ABSTRACT

The present study was performed experimentally by invitro method to examine the anti cancer activity at various concentration (62.5Î¼g/ml - 1000 Î¼g/ml) of ethanolic extract of the leaves of Cnidoscolus chayamansa against HT-29 (Colon carcinoma) cell lines using MTT assay method. From the study, it was observed that extracts showed moderate cytotoxic activity against both cancer and normal cell lines. The cytotoxicity of extracts was found to be in dose dependent and non selective as reflected by uniform CTC50 values independent of cell line origin.

Keywords: Cnidoscolus chayamansa, cytotoxicity, invitro, MTT, HT-29.

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