Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL ANALYSIS OF DASHANGA GUGGULU -AN AYURVEDIC HERBAL FORMULATION FOR HYPOTHYROIDISM

*Dr. Manisha Gupta, Anup Thakar, Mandip Goyal, Harisha C.R. and Vinay Shukla

ABSTRACT

Background: Dashanga Guggulu is indicated as one of the drugs for management of Medoroga, So for assurance of quality of polyherbal compound, pharmacognostical and pharmaceutical analysis should be done. Methods: Dashanga Guggulu was subjected to microscopic evaluation for pharmacognostical, physiochemical analysis like loss on drying, ash value, pH value, water-soluble extract, alcohol soluble extract and high-performance thin layer chromatography (HPTLC). Results: Pharmacognostical study showed the presence of certain identifying characteristics of all the ingredients of Dashanga Guggulu that is Triphala, Trikatu, Trimada and Guggulu. In the pharmaceutical study, preliminary physiochemical analysis showed that ash value 10.541%w/w, loss on drying 8.6%w/w, water soluble extract 35.63%w/w, alcohol soluble extract 15.36%w/w and HPTLC showed 4 spots in 254 nm and 13 spots in 366 nm. Conclusion: Pharmacognostical and physicochemical observations revealed the specific characters of all active constituents of Dashanga Guggulu and confirmed the purity and genuinity of the drug.

Keywords: Dashanga Guggulu, Guggulu, Hypothyroidism, Pharmacognosy, Pharmaceutical analysis.