Abstract

AUTOIMMUNE DISEASE GUILLAIN-BARRE SYNDROME: A CASE REPORT

K. Pravallika*, B. Blessy, P. Japamalai, N. Baratha Jyothi and R. Ramani

ABSTRACT

Guillain-Barré syndrome (GBS) is an acute paralysing illness usually caused by inflammation of the peripheral nerves and nerve roots. It causes tingling and numbness in the limbs as well as rapidly progressive weakness, eventually causing people to lose their ability to walk. It may affect the face and swallowing muscles, and 25% of people with GBS become so weak that they require artificial ventilation. Little is known about the long-term prognosis for patients with the severe acute motor axonal neuropathy (AMAN) form of Guillain–Barré syndrome (GBS), unlike those with acute inflammatory demyelinating neuropathy (AIDP). Here, we report a case of a young man with the acute motor axonal neuropathy (AMAN) subtype of GBS, i.e., a 34-year-old man was admitted to the hospital with a sensory-motor (demyelination than axonal) polyneuropathy consistent with the clinical diagnosis of G.B. syndrome. It is a retrospective record based study. He experienced neurological symptoms of muscle paralysis (ascending from the legs to the hands). The objective of this case report is to clarify the long term prognosis for patients with AMAN. The clinical recovery and outcome of this subject (GBS patient) were reviewed. Corticosteroids (such as prednisolone) reduce inflammation, which should reduce nerve damage. Subjects developed diabetes mellitus requiring insulin and hypertension requiring drug treatment as a result of their use of these corticosteroids.

Keywords: Guillain barre syndrome, acute motor axonal neuropathy (AMAN).