Abstract

EXTRACTION AND CHARACTERIZATION OF PHARMACEUTICAL EXCIPIENT FROM TAMARINDUS INDICA SEED

Shital S. Shinde*, Dr. A. S. Kulkarni, Shubham S. Chougule, Pooja D. Ghatage, Arbaj A. Mulla, Sambhaji V. Andure and Sushama A. Sanap

ABSTRACT

The natural polymers always have exceptional properties which make them distinct from the synthetic polymers. Tamarind Seed Polysaccharide (TSP) is one such example which shows more valuable properties making it a useful excipient for a wide range of applications. TSP is a natural polysaccharide obtained from the seeds of Tamarindus indica, recently gaining a wide potential in the field of pharmaceutical and cosmetic industries. The present research work focuses on the extraction of tamarind seed polysaccharide by ultrasound Assisted Extraction (UAE) and Chemical method. Characterization study includes Physicochemical and micromeritic properties. The results obtained from study showed that the ultrasound assisted extraction (UAE) was gives better extraction of polysaccharide from tamarind seed as compare to chemical method. Results from characterization study predict the fact that extracted polysaccharide can be used as a pharmaceutical excipient. Obtained results also showed that extracted seed polysaccharide can also be act as a binder in pharmaceutical tablets, as a humectants and emulsifier and gelling agent in the different types of formulations.

Keywords: Tamarind seed polysaccharide, Ultrasound assisted extraction (UAE), Pharmaceutical excipient.