Abstract

PHARMACOLOGICAL ACTIONS OF ALLIUM SATIVUM

C. Reddy Kumari, Syed Noori*, M. Maneesha, M. Anusha, V. Harika, K. Lekha and Kishore Babu M.

ABSTRACT

The current article discusses the applications of Allium sativum in the treatment of diabetes, a metabolic condition defined by an increase in blood sugar (hyperglycemia). In many aspects of people's day-to-day lives, products are employed as sources of medication. Sulfur compounds, which are more abundant in Allium sativum and are the basis for its therapeutic properties, are what give it its flavor. Garlic's chemical components, which reduce clots on injured endothelium and prevent platelet aggregation, have also been studied for use in the treatment of cardiovascular disease, cancer, blood pressure, atherosclerosis, and hyperlipidaemia, among other conditions. Based on customary knowledge passed down from generation to generation, it is used medicinally. Many bioactive substances, including allicin, alliin, and alliin, are present in Allium sativum. Ajoene, S-allyl-cysteine, diallyl sulphide, diallyl disulfide, and diallyl trisulfide are all components. Biomarkers are developed to determine whether individuals benefit more from garlic, because garlic and its contents can inhibit the creation, bioactivation, and proliferation of carcinogens and tumors. The development of functional foods or nutraceuticals for the prevention and treatment of specific diseases can benefit from using garlic, which is a great natural source of bioactive sulfur-containing chemicals.

Keywords: Antidiabetic, Antioxidant, Cardiovascular, Antiviral, Antifungal, Antioxidant, Antimicrobial, Antiobesity, Immunomodulation, Atherosclerosis, Anticancer, Anti-inflammatory.