Abstract

A REVIEW FLOATING TABLET

Kavita Patole*, Tejaswini Phatangare, Santosh S. Bansode and Pallavi L. Phalke

ABSTRACT

The design of floating drug delivery Systems (FDDS) should be primarily aimed to achieve more predictable and increased bioavailability. Now-a-days most of the pharmaceutical scientist is involved in developing the ideal FDDS. This ideal system should have advantage of single dose for the whole duration of treatment and it should deliver the active drug directly at the specific site. Gastric emptying occurs during fasting as well as fed states. The pattern of motility is however distinct in the 2 states. During the fasting state an interdigestive series of electrical events take anatomically the stomach is divided into 3 regions: fundus, body, and antrum (pylorus). The place, which cycle both through stomach and intestine every 2 to 3 hours.[14] This is called the interdigestive myloelectric cycle or migrating myloelectric cycle (MMC).

Keywords: Bioavailability, Gatric emptying, Interdigestive, Motility, Fundus, Myloelectric, Antrum.