Abstract

A REVIEW ON MONKEY POX VIRUS

Ravindra C. Sutar*, Bhavana S. Nalge, Sakshi C. Nalawade and Vaishnavi L. Ghorpade

ABSTRACT

Monkeypox virus was first isolated in 1959 from monkeys shipped from Singapore. The first confirmed human case of monkeypox occurred in 1970 in a child in the Democratic Republic of Congo. Human monkeypoxvirus is spreading in Europe and the US (United States). Monkeypox is spread from animals to humans through close contact with infected animals. Unlike live vaccinia virus preparations, administering modified vaccinia, Ankara does not create a skin lesion or pose a risk of local or disseminated spread. In addition, clinical trials have shown that modified vaccinia Ankara is safe and stimulates antibody production in patients with atopy and compromised immune systems, which are known contraindications to live vaccinia administration. Identifying the potential benefits and drawbacks of preventative monkeypox vaccination in endemic communities requires more thorough data collection and feasibility analysis. Access to medical care, testing capabilities, and infrastructure limits the ability to make informed decisions about best addressing this neglected tropicaldisease.

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