VALIDATED ANALYTICAL METHOD FOR THE ASSAY OF TACROLIMUS- A REVIEW
Prem Pal*, Dr. Renu Bora and Dr. Kuldeep Sharma
ABSTRACT
Tacrolimus (figure1) also known as FK506, is an immunosuppressive drug that is given orally or intravenously to people who have had a kidney, liver, heart, or other organ transplant. It is a potent drug that helps to prevent rejection of the transplanted organ by the body. In the present paper the authors have reviewed the validated analytical methods already published till now in the literature for the estimation of Tacrolimus in pharmaceutical formulations and in biological samples.
Keywords: Validated Analytical method; Tacrolimus HPLC, LC-MS/MS.
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