Abstract

MICROWAVE ASSISTED SYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND ANTIFUNGAL STUDIES OF COMPLEXES OF TRANSITION METALS WITH ASPARTAME

Ram Chandra Beniwal, Uma Rathore and N. Bhojak*

ABSTRACT

The microwave irradiation approach was used to report the synthesis, characterization and biological characteristics of complexes of novel aspartame (apm) with transition metals Mn(II), Co(II), Ni(II) and Cu(II). The structure of the compounds was discovered to be octahedral using elemental analysis, magnetic analysis, FT-IR and UV-Visible spectrum analysis. Antimicrobial tests on the ligand and its complexes against Escherichia coli, Staphylococcus aureus and Bacillus subtilis bacteria were conducted in vitro. Antifungal tests on the ligand and its complexes against C.albicans was conducted.

Keywords: Aspartame, Microwave irradiation, antimicrobial studies.