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UV-SPECTROPHOTOMETRIC ESTIMATION OF MOSAPRIDE CITRATE IN BULK AND TABLET DOSAGE FORM USING AREA UNDER CURVE METHOD
Om Yadav, K. N. Gujar, H. K. Jain*
ABSTRACT
spectrophotometric method for the estimation of Mosapride Citrate in tablet formulation using area under curve method. The standard and sample solutions of Mosapride Citrate were prepared in methanol. The area under curve in between 260 to 280 nm was measured. The method followed linearity in the range of 5-30 μg/ml with correlation coefficient value of 0.9999. This method was validated for various parameters according to ICH guideline Q2 (R1). Satisfactory values of Percent relative standard deviation for the intra-day and inter-day precision indicated that method was precise. The mean percentage recovery studies were found to be 101.13%. LOD and LOQ were calculated as 0.1032 μg/ml and 0.3129 μg/ml, respectively. Keywords: Mosapride Citrate, UV-spectrophotometry, Area under curve, Validation. [Download Article] [Download Certifiate] |