Abstract

OSTEOPOROSIS

Aishwarya S. Gandhle*, Sameer Shafi, Neha K. Pille, Monika D. Khichade, Priyanka S. Nilangekar and Sushil S. Kore

ABSTRACT

Reduction of mechanical stress on bone inhibits osteoblast-mediated bone formation and accelerates osteoclast-mediated bone organic process, and ends up in what has been referred to as decline pathology. Prolonged therapeutic bed rest, immobilization because of motor palsy from injury of the central system or peripheral nerves, application of solid to treat fractures, a standard causes of decline pathology. Imaging designation shows coarse fibrous tissue pattern and cutting of animal tissue bones. Bone metabolism markers are wont to appraise bone metabolism. From the perspective of bone metabolism, antiresorptive agents ought to be administered to inhibit bone organic process. Rehabilitation, together with bed positioning, therapeutic exercise and electrical stimulation, ought to be prescribed to subject the atrophied bone to AN acceptable level of mechanical stress. In spite of those aggressive and continuous treatments, most cases of decline pathology need an extended time for bone to recover its bone mineral density and strength. Hence, we've got to stay in mind that there aren't any treatments higher than prevention of decline pathology.

Keywords: Disuse, Osteoporosis, Bone metabolism, Treatment, Prophylaxis.