Abstract

IN SITU OPHTHALMIC GEL: A REVIEW

S. S. Anjitha*, S. Shanitha, S. Mathan and Shaiju S Dharan

ABSTRACT

Current review on in-situ gelling system explains about how sol to gel transformation occurs. The paper also briefly discusses hydrogels, which are three-dimensional structures with the ability to hold large amounts of water as well as biological fluids, causing them to swell. In situ gels are a subcategory of hydrogels that take on the characteristics of a gel when they come into contact with bodily fluids or undergo a pH change. Guar gum, gellan gum, xanthan gum, carrageenan, xyloglucan, pectin, chitosan, and thiolated chitosan are some of the polymers used in in situ gelling systems. Some of the methods for producing in situ gels are also discussed in this review.

Keywords: In situ; Ophthalmic; Hydrogel; pH triggered; Liposomes.