Abstract

ANTIOXIDANT AND OTHER NON-SURGICAL TREATMENT OF INFERTILE MEN WITH VARICOCELE

Mohammed Murad Abdullah Al-Zubaidi*

ABSTRACT

Men can have infertility for a number of reasons, and varicocele is a major one. More study is needed to determine the best way to diagnose and treat this illness. Although varicocelectomy is the most popular choice, it is not without risks, including invasion, recurrence, atrophy of the testicles, and unreliability. Despite the high price and risk, ART is a popular choice among patients with varicocele because of how simple it is to use. Invasion is only one of several ethical and moral problems that plague this technology. However, as oxidative-stress related infertility becomes more common, antioxidant therapy, which has been shown to be beneficial with minimal adverse effects, is being examined as a potential alternative. Antioxidants such bioflavonoids, carnitines, selenium, vitamins C, E, kallikrein, coenzyme Q10, cinnoxicam, zinc, and folic acid are discussed in this article. Antioxidants were found to be useful in enhancing sperm parameters and antioxidant levels, both of which are key contributors to infertility. Additionally, daflon, vitamin C, and vitamin E are helpful adjuvants to varicocelectomy. No firm evidence exists to suggest antioxidants should be used as a standard treatment or as a substitute for surgery, despite the promising potential of this approach. Therefore, in the future, larger trials supported by pregnancy outcome data are required to advocate antioxidant therapy with certainty.

Keywords: Varicocele, Male Infertility, Antioxidant Treatment, Vasectomy, Assisted Reproductive Technology.