Abstract

A PHYTOCHEMICAL EVALUATION AND REVIEW ON PHARMACOLOGICAL STUDY OF CALOTROPIS GIGANTEA

Ajay Kumar Ramdev Jaiswar*

ABSTRACT

Calotropis gigantea (Asclepiadaceae) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosides, flavonoids, terpenoids, alkaloids, tannins, & resins has been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumors and piles. Various pharmacological activities reported like analgesic activity, antipyretic activity, pregnancy interceptive activity, CNS activity, anti-inflammatory activity, procoagulant activity, antidiarrhoeal activity, free radical scavenging activity, antimicrobial activity, anti-tumor activity, antifungal activity, antitussive activity, and antifeedant activity. Calotropis gigantea contain many biologically active phytoconstituent group like cardenolides, calotnaphthalaene, steroids, tannins, glycosides, phenols, terpenoids, sugars, flavonoids, alkaloids and saponins in different part of plant including stem, root, leaves, flower etc. This plant is well-known because it generates a lot of latex. Many proteins, glycosides, tannins, and other physiologically active substances can be found in latexes. External swellings and diarrhoea are treated using the plant's leaves and aerial portions. The following provides the systematic position, common names, and vegetative characteristics of the plant. The objective of this study is to analyse the phytochemical composition of C. gigantea.

Keywords: Calotropis gigantea, Phytoconstituent, Chemical compounds, Herbal plant.