![]() |
|||||||||||||
|
All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
KETAMINE AND OPIATES: RAPID ANTIDEPRESSANT ACTION ALEN J SALERIAN MD
Alen J. Salerian MD*
ABSTRACT Major depressive disorder is a highly prevalent illness associated with significant morbidity and mortality. The N-methyl-D-aspartate receptor (NMDA) antagonist ketamine and its enantiomer S- ketamine (esketamine) - which in 2019 was approved by the FDA for treatment resistant depression - have attracted enormous interest in psychiatry by their rapid antidepressant actions, but their precise mechanism of action has remained elusive. Keywords: . [Download Article] [Download Certifiate] |