Abstract

PHYTOCONSTITUENTS ISOLATED FROM STEM BARK OF CASSIA FISTULA LINN

Anoop Agnihotri*, Vijender Singh

ABSTRACT

A detailed phytochemical study on the alcoholic extract of stem bark of Cassia fistula Linn. (Fam. Leguminoseae) led to isolation of five compounds. The structures of the five compounds were elucidated on the basis of analysis of spectroscopic data and physicochemical properties as: 1, 4, 5-trihydroxy-6, 7-dimethoxy-3-methyl-9, 10-dioxo-9, 10-dihydroanthracene-2-carboxylic acid [fistulic acid] (CF – 1), 4,5-Dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid [rhein] (CF – 2), 4, 5-dihydroxy-9, 10-dioxoanthracene-6-methyl-2-carboxylic acid [6-methylrhein] (CF – 3), (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol [+ catechin] (CF – 4) and 1,3-dihydroxy-2-methyl-5,6-dimethoxyanthraquinone (CF – 5).

Keywords: fistulic acid, rhein, 6-methyl rhein, (+) catechin, oxyanthroquinone, Cassia fistula, leguminoseae