Abstract

A REVIEW ON ALTERNATIVE APPROACHES FOR PARKINSON’S DISEASE TREATMENT

Astik*, Chitra V., Dr. Noopur Srivastava and Dr. Anjali Raj

ABSTRACT

Parkinson's disease (PD) is a neurological condition that progresses slowly over time and has both motor and nonmotor symptoms. The primary source of the disorder's motor symptoms, which include resting tremor, "cogwheel" rigidity, and bradykinesia, has been determined to be striatal dopamine deficiency. Disorders of sleep, sadness, and cognitive abnormalities are examples of nonmotor symptoms. Even though we have some symptomatic medications, particularly for the disease's motor symptoms, there are still no proven disease-modifying medications available, therefore the illness develops unchecked. We provide an overview of the various PD strategies in this paper. Where applicable, we give instances of previous or current research that have used each technique. Examples from other disorders are used to demonstrate the usefulness of any strategies that have not yet been used to treat Parkinson's disease.

Keywords: Neurodegenerative, Lewy bodies, Alpha-synuclein, Repurposing drugs.