Abstract

A REVIEW ON ANTIDIABETIC DRUGS (ALLOPATHY)

Dhonde Satish Madhukar*, Ghumare Komal Laxman, Gorde Pragati Shivaji, Hase Mayur Vasant, Ingale Shraddha Kailas and Jadhav Meghraj Dnyaneshwar

ABSTRACT

Diabetes is a metabolic disorder that occurs in the body because of decreased insulin activity and or insulin secretion. Pathological changes such as nephropathy, retinopathy, and cardiovascular complications inevitably occur in the body with the progression of the disease. Two major types of diabetes are recognized, type1and 2with type 2 diabetes (T2D) being by far the more prevalent type. As diabetes affects multiple biological functions, the use of multiple drug classes having different mode of actions is required in order to optimize therapy in diabetic patients. Five major classes of oral anti-diabetics agents (OHA) have traditionally been used for the management of patients with TD2. Mostly anti-diabetic drugs are administered orally except the insulin, exenatide, and pramlintide. There are different types of anti-diabetic drugs, and their selection depends on the nature of the diabetes, age and situation of the person, and many other factors. Treatments include the agents which increase the amount of insulin secreted by the pancreas. In the present review article summarizes in brief about drug used for treatment of diabetes mellitus.

Keywords: Diabetes, Pathophysiology, Anti-diabetic drug.