Abstract

EVALUTION OF ANALGESIC ACTIVITY OF SHOREA ROBUSTA RESINS IN SWISS ALBINO MICE

Chourasiya Vaibhav*, Anantkumar Patel, Rajendra Bapna and Dr. P. K. Dubey

ABSTRACT

Shorea robusta Gaertn. (Sal) has been commonly used in Indian traditional medicine for treatment of various ailments such as circulatory, digestive, endocrine, respiratory and skeletal systems as well as in infectious diseases. Crude extracts and isolated compounds from Shorea robusta show a wide spectrum of pharmacological activities, such as anti- inflammatory, anti-obesity, antibacterial, wound healing, anti-pyretic & analgesic activities. Many studies have provided evidence for various traditional uses. In the present study, ethanolic extract of S. robusta resin (SRE) was evaluated for its analgesic activity by making use of different central and peripheral pain models. The present review on its botany, traditional uses, pharmacological activities and phytochemistry which provides preliminary information for further studies for this potential medicinal plant. The nearness of pain implies that something isn't right. Each individual is the best judge own pain. Pain of any origin comprises an individual’s life. The analgesic activity of SRE was assessed by employing different. Materials and Methods: pain models such as, i) hot plate and tail flick tests for central analgesia.

Keywords: Analgesic, Ethanolic extract, hot plate method, tail flick method, Shorea Robusta.