SCREENING OF ENDOPHYTIC FUNGI ISOLATED FROM SOME MEDICINAL PLANTS IN JABALPUR REGION FOR ANTIBACTERIAL ACTIVITY
Diva Gupta, Rama Mandal, Jyoti Singh Puttey and Sardul S. Sandhu*
ABSTRACT
Drug resistance in bacteria, globally, has become an important issue and search for new antibacterial agent is inevitable. Endophytic fungi from medicinal plants provide a reservoir of bioactive metabolites. The present study made an attempt to isolate and screen endophytic fungi from some medicinal plants of Jabalpur region. The bioactive compounds from these fungi have tremendous antibacterial activity against five pathogenic bacteria viz. Escherichia coli, Bacillus subtilis, Salmonella typhimurium, Streptococcus pyogenes, Klebsiella pneumoniae. The isolated endophytic fungi may lead to novel natural product for use in pharmaceutical industries.
Keywords: Endophytic fungi, Microbial biodiversity, Drug resistance, Antibacterial activity.
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