Abstract

IN-VITRO ANTIOXIDANT ACTIVITIES OF METHANOLIC EXTRACT OF ROOT OF COLEUS VETTIVEROIDES (JACOB)

G.Gopalakrishnan*, C.K.Dhanapal

ABSTRACT

The aim of this study was to assess the invitro potential of methanolic extract of Root of coleus vettiveroides (Jacob). The IC50 values of methanolic extract in Hydroxyl radical scavenging activity, FRAP method were obtained to be 260 mg/ml, 140mg/ml respectively. However the IC50 values for the standard ascorbate were noted to be 440 mg/ml, 60mg/ml respectively. Measurement of total phenolic content of the methanolic extract of coleus vettiveroides (Jacob) was achieved using Folin-Phenol reagent containing 9.17 mg/g of phenolic content.The above result possess significant antioxidant activity when compare to the above all standard .The result obtained in this study clearly indicate that coleus vettiveroides (Jacob) has a significant potential to use as a natural anti-oxidant agent.

Keywords: Coleus vettiveroides (Jacob), Antioxidant, Hydroxyl radical scavenging activity, FRAP method, Estimation of Total phenolic content.