SAMPLE PREPARATION TECHNIQUES: A REVIEW
Prashant Bhadale*, Santosh Waghmare and Hemant Kamble
ABSTRACT
Bioanalysis is analytical method for determination of concentration of drugs and their metabolites present in sample. LCMS-MS is widely used for determination of drug concentration from biological samples. This article involves various techniques used for extraction of drug substance from biological sample. Paper also discuss the merits and demerits of solid phase extraction (SPE), liquid-liquid extraction (LLE).
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