Abstract

A DETAIL REVIEW ON ORODISPERSIBLE TABLETS

Rohan R. Bhutada*, Pallavi R. Khairnar, Sachin C. Joshi, Amit V. Kakad, Rupali N. Kanade and Moreshwar P. Patil

ABSTRACT

Orodispersible tablets are a novel dosage form that dissolves quickly in the mouth. This method of drug delivery is commonly used to increase patient adherence and bioavailability. Oral drug delivery and rapid tablet disintegration in the mouth without the use of water have made the orodispersible tablet the greatest alternative to traditional tablets, syrups, capsules, and other forms of medication. In the pharmaceutical business, the oral route is currently the gold standard, as it is considered the safest, most cost-effective, and most convenient way of drug delivery, resulting in the highest patient compliance. There is a range of benefits that they provide to the patient in terms of significant income from product line extensions. Oral dispersible tablets have been developed for bed rest patients, geriatric, and pediatric, as well as adults and patients who may not have access to water. Many elderly persons find it difficult to take traditional dosage forms due to hand tremors and dysphasia, so an orodispersible tablet offers an alternative. Swallowing issues can also occur in young people due to their underdeveloped muscular and nervous systems. Oral drug delivery and rapid tablet disintegration in the mouth without the use of water have made the orodispersible tablet the greatest alternative to traditional tablets, syrups, capsules, and other forms of medication. The ideal qualities, advantages, and disadvantages, as well as various manufacturing procedures and evaluation factors for orodispersible tablets, are discussed in this review paper.

Keywords: Orodispersible tablets, Freeze-Drying, Tablet Molding, Sublimation.