Abstract

REVIEW OF COMPARATIVE STUDY OF OTF WITH CONVENTIONAL DRUG DELIVERY SYSTEM

*Shravani A. Havale and Dr. Pratima S. Shinde

ABSTRACT

Fast dissolving oral films (FDOFs) are the most advanced form of oral solid dosage form due to more flexibility and comfort. It improve the efficacy of APIs by dissolving within minute in mouth after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water for administration. The FDOFs place as an alternate within the market thanks to the consumer’s preference for a fast-dissolving product over conventional tablets / capsules. The oral thin-film technology remains within the beginning stages and has bright future ahead because it fulfils all the necessity of patients. Eventually, film formulations having drug/s are going to be commercially launched using the oral film technology. However, for future growth point of view the oral thin film sector is well-positioned. In US market the OTC films of pain management and kinetosis are commercialized. More importantly, prescription OTFs have now been approved in US, EU and Japan which are the three major regions. These approved Rx films, have potential to dominate over other oral dosage forms of the same drugs. It seems that the worth of the general oral thin film market will grow significantly.

Keywords: Oral thin film (OTF), Conventional drug delivery, Oral disintegrated formulation.