Abstract

A PROSPECTIVE RANDOMIZED CONTROL STUDY TO COMPARE THE EFFICACY OF CONCENTRATED GROWTH FACTOR FOLLOWING SURGICAL REMOVAL OF IMPACTED MANDIBULAR 3rd MOLAR

R. Muralidharan, Ashish Gaur, Ankita Raj and S. Gokkulakrishnan*

ABSTRACT

Background: Surgical extraction of impacted mandibular third molar is one of the most common minor surgical procedure performed by the Oral and Maxillofacial Surgeons and with any surgical removal of impacted lower third molar always associated with postoperative complications like pain, trismus and facial swelling. There have been few attempts to study patients expectations regarding outcomes, although patients perceptions of recovery following third molar surgery. Aim: The purpose of this study is to evaluate and compare utility and efficacy of concentrated growth factor on soft t issue healing and bone healing following surgical removal of a mandibular impacted 3rdmolar with the control group. Methodology: Patients selected by means of volunteers’ recruitment process. Those interested in the surgical removal of mandibular 3 rd molars were included in the study and informed consent form was signed. All patients had moderately difficult impacted lower third molar according to modified Pederson’s index. The selected patients were divided into 2 groups of 15 patients each. Group- A- 15 patients as Control group, Group- B- 15 patients as Study group where graft was placed. Results: Concentrated growth factors is known to have higher tensile strength, higher concentration of growth factors and higher resistance to flow than Platelet rich fibrin (PRF), Platelet rich plasma( PRP),and hence compressed CGF can be used as barrier membrane with growth factors as alternative collagen membrane. This barrier membrane induces faster formation and fast tissue healing, there is much differences in bone level changes on mesial and distal side of the surgical removal of impacted teeth between two groups. Conclusion: CGF is well known to accelerate new bone formation, showed improvement in both soft tissue healing and bone formation, CGF is 100 % autologous fibrin. CGF can be used alone or with a bone graft.

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