Abstract

DETERMINANT FACTORS AND INTERVENTION TO IMPROVE ADHERENCE IN PATIENTS WITH SCHIZOPHRENIA: A SYSTEMIC REVIEW OF MEDICATION NON-ADHERENCE.

Shangeetha S.*, Pushparaj A., Jemisha J., Glady Gloria Grant C. J., Senthil Kumar N.

ABSTRACT

Non-adherence to medications is frequent in all disciplines of medicine, and patients with psychotic disorders face extra hurdles that exacerbate the problem. This is likely to affect 50% of all patients, increasing the likelihood of relapse and hospitalization. Understanding the factors that influence antipsychotic drug adherence is important since non-adherence is a major cause of psychotic relapse. Each recurrence accumulates social toxicity and disability. The most common strategies for gauging patient adherence are indirect evaluations based on efficacy and acceptability. Novel assessment methods are being developed that can directly assess adherence while simultaneously providing synchronous feedback to doctors and serving as a patient intervention. To cause a specific forecast, a negative attitude against drugs was required. There are a variety of treatment options available. Long-Acting Injectable (LAI) Antipsychotics (APs) are a theoretically beneficial strategy for ensuring adherence and minimizing symptomatic exacerbations and relapse in patients with psychotic disorders throughout the maintenance phase. Although Directly Observed Therapy (DOT) is the most common intervention, it entails direct observation and verification. Adherence-improving interventions must take into account growing intensity and changing causes. Improved determining factors affecting adherence and a novel assessment method, on the other hand, can help with early detection and management. In selecting and implementing intervention measures, it's also critical to determine the motivations for poor adherence that are unique to each patient.

Keywords: Adherence, Antipsychotics, Assessment, Medication Attitude, Interventions.