Abstract

A SHORT REVIEW ON NOVEL DRUG DELIVERY SYSTEM

*Jyoti Kumari, Dr. Hariom Sharma, Dr. Gaurav Kumar Sharma, Dr. Kaushal Kishor Chandrul

ABSTRACT

• Novel drug delivery system refers to formulations, technologies and system for transporting a pharmaceutical compound in the body as needed to safely as achieve its desired therapeutic effects. • The main aim for developing NDDS is to minimize drug degradation and loss to prevent harmful side effects and to increase bioavailability. • Various approaches involves in Novel Drug Delivery system like medical devices or drug device combination products. • Based on physical and biochemical mechanisms, NDDSs are designed. • Physical mechanism or controlled drug delivery system includes dissolution, osmosis, erosion and diffusion. • Biochemical mechanism includes gene therapy, liposomes, nanoparticles, monoclonal antibodies. • Novel drug delivery technologies have gained the importance to achieve modified delivery of herbal drugs there by increasing the therapeutic value as well as reducing toxicity. • The present reviews gives information regarding various novel techniques used for improving safety and efficacy of phytomedicines and applications of novel formulation. • Now a day recent advances in the understanding of pharmacokinetic and pharmacodynamic behaviour of drug have a more rational approache to development of optimal drug delivery system. • Now its appreciable that future success in drug delivery research will largely be result of multidisplinary efforts. • If any therapeutic agent that can be the more efficacious and safe using and improved drug delivery system represent both lucrative marketing opportunities for pharmaceutical company and advancement in the treatment of diseases of mankind. • An ideally design drug delivery system delivers a specified amount of drug to target particular site at an appropriate time and rate as dedicated by the etiological and physiological needs of the body.

Keywords: drug delivery systems, therapeutic agent, diseases, target site, body fluids, non-targeting tissues, drug etc.