Abstract

PHYSICO-CHEMICAL STANDARDIZATION OF “SAFOOF MUSAKKIN”: A PHARMACOPOEIAL UNANI COMPOUND FORMULATION

Waris Ali* and Nizamul Haque

ABSTRACT

Safoof (Powder) is one of the most important dosage form in the Unani system of medicine. Present study has been designed to study Safoof Musakkin on certain physiochemical parameters in order to determine its quality standards. The methods mentioned in National Formulary of Unani Medicine (NFUM) part II were followed for the preparation of Safoof Musakkin. Physicochemical parameters such as organoleptic properties, powder characterization, extractive value, ash value, loss of weight on drying at 105°C, pH value and TLC were investigated. The percentage values of the total ash, water soluble ash and acid insoluble ash were found to be 5.70±0.100, 1.75±0.340 and 0.966±0.088 respectively. The pH value was determined at 1% and 10% solution and the values were found to be 6.33±0.318 and 6.09±0.020 respectively. The percentage of the non successive extractive values was found to be 15.15±0.571, 14.68±0.431, 21.42±0.990 and 18.23±0.667 in petroleum ether, chloroform, ethyl alcohol and water respectively. The mean % age value of Loss of weight on drying was found to be 6.420±0.475. These findings will be useful towards establishing pharmacopoeial standards for crude drugs as well as for formulation which is gaining relevance in research on traditional medicinal system.

Keywords: Unani medicine, Sofoof Musakkin, Musakkin-e-Asab.