Abstract

INTRODUCTION, METHOD OF PREPARATION, RECENT APPLICATIONS OF NANOSTRUCTURED LIPID CARRIER SYSTEM- REVIEW

Pooja S. Niphade*, Roshani G. Bhadane and Nilima A. Thombre

ABSTRACT

Nanostructured lipid carriers are medicinal formulations made up of physiological and biocompatible lipids, as well as surfactants and co-surfactants. Modified SLN, which are nanostructured lipid carriers made of liquid lipid combined with a solid lipid to form a nanostructured solid particle matrix, have also been characterized. NLC has certain advantages over SLN in terms of regulated release. Because of their numerous favorable benefits such as skin hydration, occlusion, increased bioavailability, and skin targeting, NLCs have a high potential in the pharmaceutical and cosmetics markets. Lipid nanoparticles are a potential technique since they not only facilitate skin penetration but also avoid the limitations of traditional skin formulations. NLC are used as nanocarriers for anti-oxidants like resveratrol, tocopherol, curcumin, etc. The structure, content, multiple formulation procedures, and characterization of NLCs are all criteria for developing a stable drug delivery system, according to this review study.

Keywords: Antioxidant, Drug delivery method, Solid lipid nanoparticles, Nanostructured lipid carrier.