Abstract

POTENTIAL BIOMARKERS IN BREAST CANCER AND THE ROLE OF CHROMATOGRAPHY IN THEIR MONITORING: A REVIEW OF THE PAST DECADE

Uppuganti Sony*, U. Mounika Sarojini, Ch. Divya, D. Prasanna, Dr. K. Padmalatha

ABSTRACT

Breast cancer can occur in women of all ages and is rare in men. By 2021, there has been a pair of 3 million ladies diagnosed with carcinoma and 685,000 deaths worldwide. Its treatment depends on the stage of cancer. It is going to embody therapy, radiation, internal secretion medical care, and surgery. Therefore, biomarkers that square measure helpful for correct identification, clinical course prediction, and illness response square measure needed for clinical observation. A "biomarker" (biological marker) is an indicator of body function that can be accurately measured. Breast Carcinoma Cells (BCSCs) square measure the most culprits within the development of varied tumors and these cells square measure a significant challenge in cancer treatment. Additionally, a significant obstacle to finding an effective treatment is drug resistance. Current microRNAs (miRNAs) indicate the potential for carcinoma detection; however, existing results seem mixed. Using

Keywords: Breast cancer, Breast cancer stem cells (BCSCs), microRNAs, NCAPG, potential biomarkers, Chromatographic techniques.