Abstract

AN EMPHASIS ON POLYMERIC NANOSPONGES TO ENHANCE THE BIOAVAILABILITY OF POORLY WATER SOLUBLE DRUGS

Vipulata P. Galankar* and Dr. Ganesh D. Basarkar

ABSTRACT

Nanosponges (NS) has gained a ton of footing in drug conveyance on account of nanotechnology as of late. Researchers studying on the topic of nanotechnology can accumulate knowledge in the methods for Nanosponges characters, formulation, and applications by gathering results. They can bind with inadequately soluble drugs inside their lattice and lift their bioavailability because of their small size and permeable nature. They can be intended to target drug to explicit regions, prevents medication and protein breakdown, and control drug discharge. A list of variables that impact drug loading and discharge has been studied. In view of their benefits, Nanosponges have been read up for their restorative applications as well as in united disciplines, especially water cleansing. Nanosponges are made of three dimensional structure (3D) or scaffold with deep porous nature. The use of nanosponges, just as their arrangement strategies, formulation method and evaluation parameters, are studied in this article. Nanosponges are basic for conveying drugs in a controlled and exact way. For designated drug conveyance, a wide scope of drugs can be put into nanosponge. Lipophilic and hydrophilic nature medicament can be formulated into nanosponges.

Keywords: Nanosponges, Nanotechnology, Bioavailability, Targeted drug delivery, Lipophilic, Hydrophilic.