Abstract

STUDY ON DRUG UTILISATION& PRESCRIBING PATTERN AND USE OF ANTIBIOTICS IN THE MANAGEMENT OF DIABETIC FOOT ULCER INSURGERY WARDS OF RMMCH, ANNAMALAI UNIVERSITY.

Shalem Lakkepogu*, T.Ashwini, B.Pragna Malavika, Dr.Madhusudhan.S. ,Dr.Anvar Ali.A

ABSTRACT

The present study represents the current prescribing trend in surgery ward and it highlights certain short comings in the existing prescribing practice. A non-invasive prospective observational study was carried out surgery ward of RMMCH. Patients included were of age 20 years and above whereas pregnant women, pediatric patients, patients who are not willing to cooperate were excluded from the study. Majority of the patients in the surgery ward were diagnosed with diabetic foot ulcer (48.9%), followed by acute appendicitis. Antibiotic therapy is required for treating majority of diseases in surgery ward. 76.4% of the patients admitted in the surgery ward were cured effectively. Out of 96 patients included for the study, 60 (62.5%) were males and 36 (37.5%) were females patients, majority are of age group 35-40 [34.04%]. Among prescriptions included for the study 44 (45.83%) prescriptions had two antibiotic drugs combinations, followed by (33.33%) prescriptions had antibiotic monotheraphy. 21 (21.87%) prescriptions were found to have drug to drug interactions, out of which 17 (17.70%) had synergistic effect and 4(4.16%) had antagonist effect. 10(10.64%) prescriptions were found to have medication errors out of which 7 (7.45%) contribute dose error followed by 3 (3.19%) duplication error. Primary antibiotic therapy for management of diabetic foot includes insulin , oral anti-diabetic or combination of both. Ceftriaxone (76.8%) even though has low activity against reported higher incidence of gram positive organisms such as staphylococcus aureus and streptococcus species it is used as the first choice of drug. The antibiotics prescribed in our hospital were both from Tamilnadu Essential Drugs List (TN-EDL) and as well as out of Essential Drug List.

Keywords: prescribing pattern, surgery ward, antibiotics, ceftriaxone, diabetes mellitus, diabetic foot, essential drug list (EDL)