Abstract

FORMULATION & EVALUATION OF TOPICAL ANTIBACTERIAL HERBAL GEL OF CORIANDER AND EUCALYPTUS OIL

Jaiswal Neha R.*, Jaiswal Puja H., Patil Javesh K.

ABSTRACT

Most of the antibacterial agents were originally derived from plants. Herbal medicine refers to the use of any oil of seeds, leaves for medicinal purposes. Along with other dosage forms, herbal drugs are also formulated in the form of gel. A gel is a gelly like semisolid preparation used topically on a variety of body surfaces. The objective of the study was to formulate and evaluate the antibacterial herbal gel from the local medicinal plants. The oil of the selected plants was taken in different ratio randomly to formulate gel. The topical formulation were developed and tested for physical parameter, drug content, uniformity, Spreadibility. The result showed that coriander and eucalyptus herbal gel showed the MIC values of 50%v/v and 50 %v/v against Bacillus subtillis and staphylococcus Aureus respectively. The formulation second (ECG50) showed the maximum drug content 65% and maximum stability and zone of among the formulation.

Keywords: Antibacterial; Herbal Gel; Coriander oil, Eucalyptus oil; Formulation; Evaluation.