Abstract

FORMULATION AND DETERMINATION OF QUALITY PARAMETERS OF DIGESTIVE CHURNA WITH IMMUNITY BOOSTING PROPERTIES

Manpreet Kaur*, Amzed Khan, Shawanty and Satvinder Kaur

ABSTRACT

Ayurvedic formulation of churna is mixture of various herbs used to cure various ailments. The present study was aimed to formulate digestive churna with immunity boosting properties and to evaluate quality control parameters so that effective formulation will be achieved for gastrointestinal problems. Therefore, this study examined the beneficial effects of seven herbs formulated in Churna, which are said to have digestive properties and immunumodulator. The ingredients of churna were Ginger (Zingiber officinale), Ajowan (Trachyspermum ammi), Hing (Ferula foetida), Fennel (Foeniculum vulgare), Giloy (Tinospora cordifolia), Amla (Embelica officinalis) and Rosemary (Rosmarinus officinalis). The formulated churna derived from above said drugs is reported to have a wide range of biological activity. The finely powdered raw materials were passed through sieve number 60 and mixed in appropriate ratios. Physical parameters such as pH, foreign matter, moisture content, ash values, extractive values were determined to evaluate quality standards of plant drugs. Further phytochemical screening was also carried out to determine the constituents which have digestive activity. Phytochemical screening showed the presence of tannins, alkaloids, glycosides, flavonoids, saponins, triterpenoids, steroids, polyphenolic compounds and carbohydrates. The formulated churna was then subjected to microbiological evaluation namely for E.coli and was found to be absent which showed that the churna was free from harmful bacteria.

Keywords: Churna, Digestive, E.coli, Physical parameters, Phytochemical screening microbiological evaluation.