Abstract

THE ASSOCIATION BETWEEN CARDIAC AUTONOMIC NEUROPATHY AND DIABETES CONTROL-PROSPECTIVE STUDY AT TERTIARY CARE HOSPITAL FORM CENTRAL INDIA

Premshanker Singh*, Ritu Karoli and Shobhit Shakya

ABSTRACT

Diabetes Mellitus (DM) is one of the most common metabolic abnormalities with high morbidity and mortality rates around the world . It has chronic complications and involves various organs in body such as autonomic nervous system and cardiovascular system. The prevalence of cardiac autonomic neuropathy (CAN) in diabetic patients is about 10% in symptomatic cases and its prevalence reaches 100% in the asymptomatic cases with accurate methods such as radionuclide scan. The (CAN) without symptoms has high prevalence. It causes problems in sense of chest pain, changes in ischemic threshold, problems in ventricle systolic and diastolic function, increased chances of cardiac arrhythmia, changes in circadian rhythm of body blood pressure, cardiac events such as sudden death, infarction, exacerbation of silent myocardial ischemia and exercise intolerance. In addition, this complication has direct relationship with other diseases in diabetic patients such as small vessel disease in kidney, eye. Also, it can affect the nervous system and other organs such as digestive and genitourinary systems. The precise control of blood pressure, weight loss, treatment with hypotensive blood pressure anti-arrhythmic drugs, prevents the progression of these conditions. Also, the search for premature ventricular reperfusion, silent ischemia in patients with other risk factors for coronary artery disease prevents progression of this condition.. The diagnosis of autonomic neuropathy can be used to predict and diagnose other complications of diabetes such as gastroparesis which is difficult to diagnose.

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