Abstract

PREVALENCE OF DYSLIPIDEMIA IN PATIENTS WITH ACUTE CORONARY SYNDROME –A PROSPECTIVE STUDY IN TERTIARY CARE HOSPITAL FROM CENTRAL INDIA

Premshanker Singh*, Ritu Karoli and Mridu Singh

ABSTRACT

Dyslipidemia is an important and modifiable major risk factory in resepct of Acute Coronary Syndrome (ACS)[1,2,3,4] with an increase in total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) and decrease in high-density lipoprotein cholesterol (HDL-C)[1,2,5,6] and alone account for more than 50% of population attributable risk[2,3,7,8] Dyslipidemia is an independent and modifiable risk factor for ACS that is common in Indian population.[6,7.9.10] This study aimed to find out the prevalence of dyslipidemia within 24 hours of admission with ACS so that appropriate therapy could be started to control dyslipidemia This was a prospective study among 210 patients Out of 210 patients, 162 (77.1%) were male and 48 (22.9%) were female. The mean age was 59.19±12.69 years. 128 (61%) participants had ST Elevation Myocardial Infarction (STEMI), 54 (25.7%) Non ST Elevation Myocardial Infarction (NSTEMI) and 28 (13.3%) Unstable Angina (USA). Hypertension was present in 70 (33.3%) and was the most frequently observed risk factor followed by 54 (25.7%) patients were overweight or obese, 44 (10.5%) patients were smokers, 5.7% had a family history of CAD and 4.8% had a history of significant alcohol consumption Study was conducted in 210 admitted patients diagnosed as Acute Coronary Syndrome (ACS) at Dr RML Institute of medical sciences, Lucknow, India-226010 There is a lower prevalence of high LDL-C and a high prevalence of lower HDL-C levels among the Indian population. Although Indian patients are likely to benefit from lowering LDL-C, the threshold for treatment and targets seem to be lower. These thresholds and targets need to be determined by larger studies and by our guidelines for Indian population.

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