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Abstract

DELETERIOUS EFFECTS OF DAIDZEIN ON THE FERTILITY OF MALE RATS

Reham M. Morsi*, Salah-Ahmed E.M. and Mobasher E.E.

ABSTRACT

Daidzein, is naturally occurring isoflavone, which is classed as a phytoestrogen because it possesses estrogen-like properties. To account for potential reproductive effects, the aim of the current work was designed to investigate the impact of daizein administration in different doses on fertility of male albino rats. Eighty male rats were randomly divided into four groups of twenty rats each. Groups were located as normal control and three other groups which received 25, 50 and 100mg daizein/kg b.wt/day respectively. The levels of serum total & free testosterone, dihydrotestosterone, LH and FSH as well as antioxidant and lipid peroxidation in testis tissue were determined after one and two months of treatment. The results revealed a significant (p

Keywords: Phytoestrogen, Daidzein, Fertility, Testis, Rats.


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