Abstract

ROLE OF CAPSAICIN IN THE REPAIR OF CELLULAR ACTIVITY IN MICE LIVER

Sarule Maharudra Balaji*, 1Bavage S. B. and 2Ajgunde B. R.

ABSTRACT

This study aimed to determine the efficacy of capsaicin in Kupffer cells, polymorphonuclear, stellate, and fibroblast cells in the liver of mice made of aflatoxin B1. 20 mice were used as a sample, distributed in four groups (T0) given 0.5 ml of polyethylene glycol, (T1) given 0.5 ml of capsaicin + 0.5 ml of polyethylene glycol, (T2) controlled by 0.1 ml of aflatoxin B1 + 0.5 ml of polyethylene glycol, (T3) was given 0.1 ml of aflatoxin B1 + 0,5 ml of capsaicin, respectively. All treatments are performed month and then followed by liver dissociation of hematoxylin eosin staining. Different cells are listed then analyzed using ANOVA and Tukey for multiple comparisons testing (p

Keywords: Animal, Capsaicin, Kupffer cell, Stellate, Fibroblast, aflatoxin B1.