Abstract

PHYTOCHEMICAL SCREENING AND ANTHELMINTHIC ACTIVITY OF CANTHIUM PARVIFLORUM ROOTS

Krishna B*, Sanjeeva Kumar A, Praneetha R, Rathnakar E, Venkata RamanaMurthy B, Pavan Kumar G

ABSTRACT

The main aim of the study was to investigate phytoconstituents present and anthelminthic activity in the Canthium parviflorum root. Extraction was carried out by continuous hot percolation method using ethyl acetate and methanol a solvents. Both the extracts were subjected to phytochemical screening using standards methods, where as in-vitro anthelminthic method was evaluated at three different concentrations using Pheretima posthuma as test organism, the parameters like the time of paralysis and the time of death were determined .The extract showed significant activity in the dose dependent manner and especially in methanolic root extract showed significant activity than that of standard drug piperazine citrate. This might due to the presence of secondary metabolites like tannins and alkaloids which may be responsible for the activity.

Keywords: Phytochemical screening, Canthium parviflorum, anthelminthic activity, Pheretima posthuma.